Medication

Anusol ointment

UGX 34,000

Symptomatic relief of uncomplicated internal and external haemorrhoids, pruritus ani, proctitis and fissures. Also indicated post operatively in ano- rectal surgical procedures and after incision of thrombosed or sclerosed ano- rectal veins.

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Description

Qualitative and quantitative composition

Each 100g ointment contains:

For full list of excipients, see section 6.1

Pharmaceutical form

A light buff coloured ointment.

 Therapeutic indications

Symptomatic relief of uncomplicated internal and external haemorrhoids, pruritus ani, proctitis and fissures. Also indicated post operatively in ano- rectal surgical procedures and after incision of thrombosed or sclerosed ano- rectal veins.

Anusol Ointment provides antiseptic, astringent and emollient properties which help to relieve discomfort associated with minor ano-rectal conditions.

Posology and method of administration

Topical.

Adults and Elderly (over 65 years): Apply to the affected area at night, in the morning and after each evacuation until the condition is controlled. Thoroughly cleanse the affected area, dry and apply ointment. Anusol Ointment should be applied on a gauze dressing. For internal conditions use rectal nozzle provided. Remove the nozzle cap. Clean the nozzle after each use. Not to be taken orally.

Children: Not recommended

 Contraindications

Hypersensitivity to the active substance(s) or to any of the excipients listed in section 6.1

 Special warnings and precautions for use

Patients with rectal bleeding or blood in the stool should talk to their doctor before using this product as these conditions may be the symptom of a more serious underlying disorder.

If symptoms persist or worsen, patients should be instructed to stop use and consult a physician.

 Interaction with other medicinal products and other forms of interaction

None known.

 Fertility, pregnancy and lactation

Whilst formal studies on the effect of this product during pregnancy have not been conducted, there is no epidemiological evidence of adverse effects either to the pregnant mother or foetus.

This product should not be used during pregnancy and lactation unless the potential benefit of treatment to the mother outweighs the possible risk to the developing foetus or nursing infant.

 Effects on ability to drive and use machines

None known.

Undesirable effects

No Adverse Drug Reactions (ADRs) have been identified from the analysis of post-marketing data for fixed combinations of Balsam Peru, bismuth oxide and zinc oxide.

ADRs identified during Post-Marketing experience with Zinc Oxide (topical use) are included in the Table below. The frequencies are provided according to the following convention

Very common ≥1/10

Common ≥1/100 and < 1/10

Uncommon ≥1/1,000 and <1/100

Rare ≥1/10,000 and <1/1,000

Very rare <1/10,000

Not known (cannot be estimated from the available data)

Adverse Reactions are presented by frequency category based on 1) incidence in adequately designed clinical trials or epidemiology studies, if available, or 2) when incidence cannot be estimated, frequency category is listed as ‘Not known’.

Other adverse reactions include: Skin sensitization reactions and systemic contact dermatitis, attributed directly to Balsam Peru have been reported in published literature

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.

Overdose

No overdose related adverse drug reactions have been identified from the post- marketing data analysis of Balsam Peru, bismuth oxide, and zinc oxide.

The ingestion of topical zinc oxide can potentiate gastrointestinal symptoms like stomach pain, nausea, vomiting, and diarrhoea.

Symptoms of acute oral overdose of bismuth-containing preparations may include nausea, vomiting, renal failure and rarely liver damage. Encephalopathy and discolouration of mucous membranes may occur with chronic overdose.

No cases of Balsam Peru overdose have been identified in the medical literature.

Treatment of a large acute overdose should include gastric lavage, purgation with magnesium sulphate and complete bed rest. If necessary, apply oxygen and give general supportive measures.

Pharmacological properties

Pharmacodynamic properties

Pharmacotherapeutic group: Other agents for treatment of haemorrhoids and anal fissures for topical use, ATC code: C05AX

Anusol Ointment provides antiseptic, astringent and emollient properties which help to relieve discomfort associated with minor ano-rectal conditions.

Bismuth Oxide is weakly astringent with supposed antiseptic properties and has a protective action on mucous membranes and raw surfaces.

Zinc Oxide is an astringent and mild antiseptic and probably owes its actions to the ability of the zinc ion to precipitate protein but other mechanisms may be involved. Zinc Oxide is also used to absorb skin moisture and decrease friction and discourage growth of certain bacteria.

Balsam Peru has a very mild antiseptic action by virtue of its content of cinnamic and benzoic acids. It is believed to promote the growth of epithelial cells.

Pharmacokinetic properties

The active ingredients exert their therapeutic effect without being absorbed into the systemic circulation. These observations are supported by evidence from various studies and reviews.

Preclinical safety data

The active ingredients of Anusol are well known constituents of medicinal products and their safety profile is well documented.

Pharmaceutical particulars

List of excipients

Anusol Ointment contains the following excipients: –

Magnesium stearate

Cocoa butter

Lanolin anhydrous

Castor oil

Incompatibilities

None known.

 Shelf life

Not less than 3 years when stored in the original packing.

Special precautions for storage

Do not store above 25° C.

For storage conditions after first opening of the medicinal product, see section 6.3.

Not all pack sizes may be marketed

Special precautions for disposal and other handling

No special requirements.

Any unused medicinal product or waste material should be disposed of in accordance with local requirements

Quick Comparison

Settings	Anusol ointment remove	Botanical Hand Sanitizer Gel remove	Sonatec MouthWash- Alcohol Free 250ml remove	Fibo Powder Sachets 10’s remove	Fibo Syrup remove	Enemax Enema- 120ml remove
Name	Anusol ointment remove	Botanical Hand Sanitizer Gel remove	Sonatec MouthWash- Alcohol Free 250ml remove	Fibo Powder Sachets 10’s remove	Fibo Syrup remove	Enemax Enema- 120ml remove
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SKU		SF1113569600-7-7
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Price	UGX 34,000	UGX 14,000	UGX 20,000	UGX 15,000	UGX 13,000	UGX 20,000
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Description	Symptomatic relief of uncomplicated internal and external haemorrhoids, pruritus ani, proctitis and fissures. Also indicated post operatively in ano- rectal surgical procedures and after incision of thrombosed or sclerosed ano- rectal veins.	Soft and non-irritating, does not hurt the skin, has a water retention and hydration function	Sonatec mouthwash contains Cetylpyridinium Chloride and has antiseptic properties intended to reduce the microbial growth in the oral cavity, mild infections of the mouth and throat and associated bad breath, gingivitis and the control of plaque.	Product Name: Fibo Powder Sachet 10’sProduct Form: Powder Pack Size: 10’s Marketed By: Hinucon Generic Category: Herbal Preparation Ingredients: Wheat Dextrin and Green Tea Extract	Uses This is herbal preparation used to prevent constipation and also prevents excessive fats in body by fasting metabolism. Side Effects Gas or stomach cramping may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. When not to use It is contraindicated in patients with known hypersensitivity to the drug	Enemax enema is used for Constipation, Additive for parenteral fluid formulas, Hypophosphatemia, and other conditions. Enemax enema may also be used for purposes not listed in this medication guide. Enemax enema contains Disodium Phosphate and Mono Sodium Phosphate as active ingredients. Enemax enema works by possessing the laxative action; maintaining the red cell glucose utilization and lactate production Side-effects: The following is a list of possible side-effects that may occur from all constituting ingredients of Enemax enema. This is not a comprehensive list. These side-effects are possible but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away. Stomach pain Hyperkalemia Nausea Vomiting Confusion Dizziness Muscle cramps Numbness Tingling Weakness in hands or feet Precautions: Before using Enemax enema, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below. patients with a history of seizures patients with cardiac failure patients with cirrhosis patients with inflammatory bowel disease Interactions with Enemax enema: If you use other drugs or over the counter products at the same time, the effects of Enemax enema may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that your doctor can help you prevent or manage drug interactions. Enemax enema may interact with the following drugs and products: Aluminum and/or magnesium-containing antacids Cyclosporine Heparin When not to use Enemax enema: Hypersensitivity to Enemax enema is a contraindication. In addition, Enemax enema should not be used if you have the following conditions: hypernatremia older age patients patients with bowel obstruction patients with impaired renal function patients with infected stones patients with poor gut motility Missing a dose: In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra doses to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently. Overdosage of Enemax enema: Do not use more than the prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Enemax enema, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with the necessary information. Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage. Please consult your physician or pharmacist or product package for more information. Storage of Enemax enema: Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets. Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Enemax enema.
Content	Qualitative and quantitative compositionEach 100g ointment contains: Zinc Oxide 10.75 g Bismuth Subgallate 2.25 g Balsam Peru 1.875 g Bismuth Oxide 0.875 g For full list of excipients, see section 6.1Pharmaceutical formA light buff coloured ointment. Therapeutic indicationsSymptomatic relief of uncomplicated internal and external haemorrhoids, pruritus ani, proctitis and fissures. Also indicated post operatively in ano- rectal surgical procedures and after incision of thrombosed or sclerosed ano- rectal veins.Anusol Ointment provides antiseptic, astringent and emollient properties which help to relieve discomfort associated with minor ano-rectal conditions.Posology and method of administrationTopical.Adults and Elderly (over 65 years): Apply to the affected area at night, in the morning and after each evacuation until the condition is controlled. Thoroughly cleanse the affected area, dry and apply ointment. Anusol Ointment should be applied on a gauze dressing. For internal conditions use rectal nozzle provided. Remove the nozzle cap. Clean the nozzle after each use. Not to be taken orally.Children: Not recommended ContraindicationsHypersensitivity to the active substance(s) or to any of the excipients listed in section 6.1 Special warnings and precautions for usePatients with rectal bleeding or blood in the stool should talk to their doctor before using this product as these conditions may be the symptom of a more serious underlying disorder.If symptoms persist or worsen, patients should be instructed to stop use and consult a physician. Interaction with other medicinal products and other forms of interactionNone known. Fertility, pregnancy and lactationWhilst formal studies on the effect of this product during pregnancy have not been conducted, there is no epidemiological evidence of adverse effects either to the pregnant mother or foetus.This product should not be used during pregnancy and lactation unless the potential benefit of treatment to the mother outweighs the possible risk to the developing foetus or nursing infant. Effects on ability to drive and use machinesNone known.Undesirable effectsNo Adverse Drug Reactions (ADRs) have been identified from the analysis of post-marketing data for fixed combinations of Balsam Peru, bismuth oxide and zinc oxide.ADRs identified during Post-Marketing experience with Zinc Oxide (topical use) are included in the Table below. The frequencies are provided according to the following conventionVery common ≥1/10Common ≥1/100 and < 1/10Uncommon ≥1/1,000 and <1/100Rare ≥1/10,000 and <1/1,000Very rare <1/10,000Not known (cannot be estimated from the available data)Adverse Reactions are presented by frequency category based on 1) incidence in adequately designed clinical trials or epidemiology studies, if available, or 2) when incidence cannot be estimated, frequency category is listed as 'Not known'. System Organ Class (SOC) Frequency Adverse Drug Reaction(Preferred Term) Immune System Disorders Rare Hypersensitivity General Disorders and Administration site conditions Not known Application site reactions (including Burn, erythema, Exfoliation, Irritation, Pain, Pruritus, Rash and Urticaria) Other adverse reactions include: Skin sensitization reactions and systemic contact dermatitis, attributed directly to Balsam Peru have been reported in published literatureReporting of suspected adverse reactionsReporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.OverdoseNo overdose related adverse drug reactions have been identified from the post- marketing data analysis of Balsam Peru, bismuth oxide, and zinc oxide.The ingestion of topical zinc oxide can potentiate gastrointestinal symptoms like stomach pain, nausea, vomiting, and diarrhoea.Symptoms of acute oral overdose of bismuth-containing preparations may include nausea, vomiting, renal failure and rarely liver damage. Encephalopathy and discolouration of mucous membranes may occur with chronic overdose.No cases of Balsam Peru overdose have been identified in the medical literature.Treatment of a large acute overdose should include gastric lavage, purgation with magnesium sulphate and complete bed rest. If necessary, apply oxygen and give general supportive measures.Pharmacological propertiesPharmacodynamic propertiesPharmacotherapeutic group: Other agents for treatment of haemorrhoids and anal fissures for topical use, ATC code: C05AXAnusol Ointment provides antiseptic, astringent and emollient properties which help to relieve discomfort associated with minor ano-rectal conditions.Bismuth Oxide is weakly astringent with supposed antiseptic properties and has a protective action on mucous membranes and raw surfaces.Zinc Oxide is an astringent and mild antiseptic and probably owes its actions to the ability of the zinc ion to precipitate protein but other mechanisms may be involved. Zinc Oxide is also used to absorb skin moisture and decrease friction and discourage growth of certain bacteria.Balsam Peru has a very mild antiseptic action by virtue of its content of cinnamic and benzoic acids. It is believed to promote the growth of epithelial cells.Pharmacokinetic propertiesThe active ingredients exert their therapeutic effect without being absorbed into the systemic circulation. These observations are supported by evidence from various studies and reviews.Preclinical safety dataThe active ingredients of Anusol are well known constituents of medicinal products and their safety profile is well documented.Pharmaceutical particularsList of excipientsAnusol Ointment contains the following excipients: -Magnesium stearateCocoa butterLanolin anhydrousCastor oilIncompatibilitiesNone known. Shelf lifeNot less than 3 years when stored in the original packing.Special precautions for storageDo not store above 25° C.For storage conditions after first opening of the medicinal product, see section 6.3.Not all pack sizes may be marketedSpecial precautions for disposal and other handlingNo special requirements.Any unused medicinal product or waste material should be disposed of in accordance with local requirements	The hand cleaner is an Non-irritating Refreshing Hand Spray Hand Sanitizer that kills dirty stuff on contact! This clearner formula stops the spread of dirty stuff to keep your family safe. Safe for babies. This hand sanitizer is the perfect solution for hand hygiene at home, the office, medical facilities or while you travel. It stops the transition of dirty stuff and cleanses your skin. You can easily control the quantity. Small size, easy to carry. Do not wash with water, easy to save water. Keep clean hands and health for kids. Better yet, it won't leave a sticky or tacky residue like other hand sanitizers. Make you easily can keep clean and tidy anytime and anywhere. It is an interesting washing product, environmental protection, travel products. A good partner for your health. Soft and non-irritating, does not hurt the skin, has a water retention and hydration function. Small size, easy to carry. Gel texture, you can easily control the amount. The Hand Sanitizer Gel is perfect for all occasions, this Hands Sterilizer Gel is convenient and easy to use. These size bottles are perfect and practical to carry in school bags, bags, travel bags, etc.	Sonatec mouthwash contains Cetylpyridinium Chloride and has antiseptic properties intended to reduce the microbial growth in the oral cavity, mild infections of the mouth and throat and associated bad breath, gingivitis and the control of plaque.	Fibo, a product of European origin, is a source of soluble fiber. It also contains benefits of green tea extract. Fibo helps to prevent constipation, regulate bowel and digestion, reduce cholesterol, and maintain healthy weight. Fibo is very convenient for daily use as it dissolves completely in water. It can also be used in many hot and cold beverages.	Fibo Syrup is a pleasant tasting ready-to-take liquid fiber for the treatment and prevention from Constipation. Fibo Syrup conveniently helps fulfill daily fiber needs in all age groups. It is effective in regulating bowel movement and digestion. The ingredient in Fibo Syrup is well researched and documented.
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Additional information		size 250ml type-of-packing Bottle quantity-per-case 1